Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNK2 All Species: 15.15
Human Site: S523 Identified Species: 41.67
UniProt: Q9Y3S1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3S1 NP_006639.3 2297 242676 S523 E S G F F H E S D V K I V A K
Chimpanzee Pan troglodytes XP_001150671 2354 247864 G549 E S G Y V C E G D H K T M A K
Rhesus Macaque Macaca mulatta XP_001108626 2142 225829 S508 E S G F F H E S D V K I V A K
Dog Lupus familis XP_853960 2389 250985 G554 E S G Y V C E G D H K T M A K
Cat Felis silvestris
Mouse Mus musculus Q3UH66 2149 227509 S523 D S G F F H E S D V K I V A K
Rat Rattus norvegicus Q9JIH7 2126 225198 S443 T S G V K P A S F D K V A I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508024 2425 260713 S630 E S G F F H E S D V K I V A K
Chicken Gallus gallus XP_414326 2183 235443 A418 K S I R D R V A L I L W R R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344215 2001 216452 F392 S G V K P A S F C K V A V P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.7 86.9 29.1 N.A. 76 29.7 N.A. 55 54.5 N.A. 38.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 43 87.9 42.4 N.A. 79.9 43.4 N.A. 64.4 63.6 N.A. 50.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 53.3 N.A. 93.3 26.6 N.A. 100 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 66.6 N.A. 100 33.3 N.A. 100 33.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 12 12 0 0 0 12 12 67 0 % A
% Cys: 0 0 0 0 0 23 0 0 12 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 12 0 0 0 67 12 0 0 0 0 0 % D
% Glu: 56 0 0 0 0 0 67 0 0 0 0 0 0 0 23 % E
% Phe: 0 0 0 45 45 0 0 12 12 0 0 0 0 0 0 % F
% Gly: 0 12 78 0 0 0 0 23 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 45 0 0 0 23 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 12 0 45 0 12 0 % I
% Lys: 12 0 0 12 12 0 0 0 0 12 78 0 0 0 67 % K
% Leu: 0 0 0 0 0 0 0 0 12 0 12 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 12 0 0 0 0 0 0 0 12 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 12 0 12 0 0 0 0 0 0 12 12 0 % R
% Ser: 12 89 0 0 0 0 12 56 0 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % T
% Val: 0 0 12 12 23 0 12 0 0 45 12 12 56 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 23 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _